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dc.contributor.authorDincol, G.
dc.contributor.authorUslu, B.
dc.contributor.authorDiz-Kucukkaya, R.
dc.contributor.authorDogan, O.
dc.contributor.authorAgan, M.
dc.date.accessioned2021-03-04T09:20:01Z
dc.date.available2021-03-04T09:20:01Z
dc.date.issued2006
dc.identifier.citationDincol G., Agan M., Dogan O., Diz-Kucukkaya R., Uslu B., "T-cell-rich B-cell lymphoma of the spleen presenting with severe hypersplenism", CLINICAL AND LABORATORY HAEMATOLOGY, cilt.28, sa.6, ss.419-422, 2006
dc.identifier.issn0141-9854
dc.identifier.othervv_1032021
dc.identifier.otherav_67b90c10-b8c1-492d-bc42-eb78d6f9bb36
dc.identifier.urihttp://hdl.handle.net/20.500.12627/71984
dc.identifier.urihttps://doi.org/10.1111/j.1365-2257.2006.00828.x
dc.description.abstractWe report a 19-year-old woman who was presented with B-symptoms, massive splenomegaly, hepatomegaly and hypersplenism. She underwent diagnostic/therapeutic splenectomy. Microscopically, the spleen showed a vaguely micronodular and diffuse proliferation of lymphoid cells in the white pulp that also involved the red pulp. On immunohistochemical staining, this proliferation consisted predominantly of CD3(+), CD7(+) small T cells with the presence of a minor population of CD15(-),CD30(-), CD20(+) large atypical B cells. A liver biopsy also showed a similar morphology to that seen in the spleen. After splenectomy, only the pancytopenia improved. A combined immunochemotherapy regimen (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone) was utilized, which resulted in a complete remission.
dc.language.isoeng
dc.subjectHEMATOLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectHematoloji
dc.titleT-cell-rich B-cell lymphoma of the spleen presenting with severe hypersplenism
dc.typeMakale
dc.relation.journalCLINICAL AND LABORATORY HAEMATOLOGY
dc.contributor.department, ,
dc.identifier.volume28
dc.identifier.issue6
dc.identifier.startpage419
dc.identifier.endpage422
dc.contributor.firstauthorID180435


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