Sex-specific associations of TCF7L2 variants with fasting glucose, type 2 diabetes and coronary heart disease among Turkish adults

Date
2020
Author
Lehtimäki, Terho
Kömürcü-Bayrak, Evrim
Onat, Altan
Can, Gunay
Mononen, Nina
Kähönen, Mika
Laaksonen, Reijo
Erginel-Ünaltuna, Nihan
Yüzbaşıoğulları, Ayşe Berna
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Abstract
Objective: TCF7L2 is a repressor and transactivator of genes, and its variants are strongly associated with diabetes. This study aimed to evaluate the sex-specific relationship between the most common TCF7L2 gene variants (-98368G>T, rs12255372 and -47833C>T, rs7903146) with diabetes and coronary heart disease in Turkish Adult Risk Factor (TARF) Study.
URI
http://hdl.handle.net/20.500.12627/72673
https://doi.org/10.14744/anatoljcardiol.2020.57736
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