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The effects of age and gender on the relationship between HMGCR promoter-911 SNP (rs33761740) and serum lipids in patients with coronary heart disease

dc.contributor.authorAkadam-Teker, Basak
dc.contributor.authorYilmaz-Aydogan, Hülya
dc.contributor.authorOzturk, Oguz
dc.contributor.authorBugra, Zehra
dc.contributor.authorTeker, Erhan
dc.contributor.authorCakmak, Huseyin Altug
dc.contributor.authorKucukhuseyin, Ozlem
dc.contributor.authorDaglar-Aday, Aynur
dc.contributor.authorCoskunpinar, Ender
dc.contributor.authorKurnaz, Özlem
dc.date.accessioned2021-03-04T09:39:46Z
dc.date.available2021-03-04T09:39:46Z
dc.identifier.citationAkadam-Teker B., Kurnaz Ö., Coskunpinar E., Daglar-Aday A., Kucukhuseyin O., Cakmak H. A. , Teker E., Bugra Z., Ozturk O., Yilmaz-Aydogan H., "The effects of age and gender on the relationship between HMGCR promoter-911 SNP (rs33761740) and serum lipids in patients with coronary heart disease", GENE, cilt.528, ss.93-98, 2013
dc.identifier.issn0378-1119
dc.identifier.otherav_69497f65-2277-405e-a58f-87be71f81a6e
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/72961
dc.identifier.urihttps://doi.org/10.1016/j.gene.2013.07.056
dc.description.abstractBackground: Hydroxymethylglutaryl-Coenzyme A Reductase (HMGCR) catalyzes the rate-limiting step of cholesterol biosynthesis. This enzyme is the target of the widely available cholesterol lowering statins. In this population-based case-control study, the frequencies of -911 C>A polymorphism (rs3761740) of the HMGCR gene in patients with coronary heart disease (CHD) and healthy subjects were investigated and the correlations between the different genotypes and hypercholesterolemia with cardiovascular risk factors were analyzed.
dc.language.isoeng
dc.subjectHealth Sciences
dc.subjectTıbbi Genetik
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectTemel Bilimler
dc.subjectGenetics
dc.subjectMolecular Biology
dc.subjectGenetics (clinical)
dc.subjectLife Sciences
dc.subjectGENETİK VE HAYAT
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.titleThe effects of age and gender on the relationship between HMGCR promoter-911 SNP (rs33761740) and serum lipids in patients with coronary heart disease
dc.typeMakale
dc.relation.journalGENE
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume528
dc.identifier.startpage93
dc.identifier.endpage98
dc.contributor.firstauthorID2370239


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