dc.contributor.author | Demir, Kadir | |
dc.contributor.author | Cakaloglu, Yilmaz | |
dc.contributor.author | Kaymakoglu, Sabahattin | |
dc.contributor.author | Besisik, Fatih | |
dc.contributor.author | Akyuz, Filiz | |
dc.contributor.author | UYANIKOĞLU, AHMET | |
dc.contributor.author | Danalioglu, Ahmet | |
dc.contributor.author | Ermis, Fatih | |
dc.contributor.author | Pinarbasi, Binnur | |
dc.date.accessioned | 2021-03-04T10:12:26Z | |
dc.date.available | 2021-03-04T10:12:26Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | UYANIKOĞLU A., Kaymakoglu S., Danalioglu A., Akyuz F., Ermis F., Pinarbasi B., Demir K., Besisik F., Cakaloglu Y., "Durability of sustained virologic response in chronic hepatitis C", Gut and Liver, cilt.7, sa.4, ss.458-461, 2013 | |
dc.identifier.issn | 1976-2283 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_6c09abff-3c18-4dab-b046-c98976fa5c39 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/74697 | |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84880302539&origin=inward | |
dc.identifier.uri | https://doi.org/10.5009/gnl.2013.7.4.458 | |
dc.description.abstract | Background/Aims: The aim of this study is to investigate the rate of sustained virologic response (SVR) in chronic hepatitis C patients receiving antiviral treatment. Methods: The files of patients with chronic hepatitis C treated with interferon ribavirin between 1995 and 2009 were reviewed retrospectively. Six months after the end of treatment, patients with negative hepatitis C virus (HCV)-RNA (<50 IU/mL, as determined by the polymerase chain reaction method) were enrolled in the study. Results: The mean age of 196 patients (89 males) was 46.13 +/- 11.10 years (range, 17 to 73 years). In biopsies, the mean stage was 1.50 +/- 0.94; histological activity index was 7.18 +/- 2.43. In total, 139 patients received pegylated interferon (IFN)+ribavirin, 21 patients received classical IFN+ribavirin, and 36 patients received IFN alone. The HCV genotypes of 138 patients were checked: 77.5% were genotype 1b, and 22.5% were other genotypes. After achievement of SVR, the median follow-up period was 33.5 months (range, 6 to 112 months), and in this period relapse was only detected in two patients (1.02%) at 18 and 48 months after treatment. Conclusions: In total, 98.9% of patients with SVR in chronic hepatitis C demonstrated truly durable responses over the long-term follow-up period of 3 years; relapsed patients had intermittent or low-grade viremia. | |
dc.language.iso | eng | |
dc.subject | Gastroenteroloji-(Hepatoloji) | |
dc.subject | İç Hastalıkları | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | GASTROENTEROLOJİ VE HEPATOLOJİ | |
dc.title | Durability of sustained virologic response in chronic hepatitis C | |
dc.type | Makale | |
dc.relation.journal | Gut and Liver | |
dc.contributor.department | Harran Üniversitesi , Tıp Fakültesi , İç Hastalıkları Anabilim Dalı | |
dc.identifier.volume | 7 | |
dc.identifier.issue | 4 | |
dc.identifier.startpage | 458 | |
dc.identifier.endpage | 461 | |
dc.contributor.firstauthorID | 210055 | |