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dc.contributor.authorTamimi, Rulla M.
dc.contributor.authorPerez-Gomez, Beatriz
dc.contributor.authorPollan, Marina
dc.contributor.authorMaskarinec, Gertraud
dc.contributor.authorGiles, Graham
dc.contributor.authorHopper, John
dc.contributor.authorStone, Jennifer
dc.contributor.authorRajaram, Nadia
dc.contributor.authorTeo, Soo-Hwang
dc.contributor.authorMariapun, Shivaani
dc.contributor.authorYaffe, Martin J.
dc.contributor.authorBurton, Anya
dc.contributor.authorDos-Santos-Silva, Isabel
dc.contributor.authorHipwell, John H.
dc.contributor.authorDickens, Caroline
dc.contributor.authorHartman, Mikael
dc.contributor.authorLee, Charmaine Pei Ling
dc.contributor.authorChiah, Kee-Seng
dc.contributor.authorOzmen, Vahit
dc.contributor.authorAribal, Mustafa Erkin
dc.contributor.authorFlugelman, Anath Arzee
dc.contributor.authorLajous, Martin
dc.contributor.authorLopez-Riduara, Ruy
dc.contributor.authorRice, Megan
dc.contributor.authorRomieun, Isabelle
dc.contributor.authorUrsin, Giske
dc.contributor.authorQureshi, Samera
dc.contributor.authorMa, Huiyan
dc.contributor.authorLee, Eunjung
dc.contributor.authorVan Gils, Carla H.
dc.contributor.authorWanders, Johanna O. P.
dc.contributor.authorVinayak, Sudhir
dc.contributor.authorNdumia, Rose
dc.contributor.authorSchuez, Joachim
dc.contributor.authorLinton, Linda
dc.contributor.authorBoyd, Norman F.
dc.contributor.authorSalem, Dorria
dc.contributor.authorChiarelli, Anna M.
dc.contributor.authorKamal, Rasha
dc.contributor.authorMccormack, Valerie A.
dc.contributor.authorAllen, Steve
dc.contributor.authorVinnicombe, Sarah
dc.contributor.authorMoss, Sue
dc.contributor.authorLee, Jong Won
dc.contributor.authorKim, Jisun
dc.contributor.authorPereira, Ana
dc.contributor.authorGarmendia, Maria Luisa
dc.contributor.authorSirous, Reza
dc.contributor.authorSirous, Mehri
dc.contributor.authorPeplonska, Beata
dc.contributor.authorBukowska, Agnieszka
dc.contributor.authorBertrand, Kimberly
dc.contributor.authorNagata, Chisato
dc.contributor.authorKwong, Ava
dc.contributor.authorVachon, Celine
dc.contributor.authorScott, Christopher
dc.date.accessioned2021-03-04T10:24:11Z
dc.date.available2021-03-04T10:24:11Z
dc.identifier.citationMccormack V. A. , Burton A., Dos-Santos-Silva I., Hipwell J. H. , Dickens C., Salem D., Kamal R., Hartman M., Lee C. P. L. , Chiah K., et al., "International Consortium on Mammographic Density: Methodology and population diversity captured across 22 countries", CANCER EPIDEMIOLOGY, cilt.40, ss.141-151, 2016
dc.identifier.issn1877-7821
dc.identifier.otherav_6d0490fa-e16d-4142-96b0-499fa5cc2576
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/75327
dc.identifier.urihttps://doi.org/10.1016/j.canep.2015.11.015
dc.description.abstractMammographic density (MD) is a quantitative trait, measurable in all women, and is among the strongest markers of breast cancer risk. The population-based epidemiology of MD has revealed genetic, lifestyle and societal/environmental determinants, but studies have largely been conducted in women with similar westernized lifestyles living in countries with high breast cancer incidence rates. To benefit from the heterogeneity in risk factors and their combinations worldwide, we created an International Consortium on Mammographic Density (ICMD) to pool individual-level epidemiological and MD data from general population studies worldwide. ICMD aims to characterize determinants of MD more precisely, and to evaluate whether they are consistent across populations worldwide. We included 11755 women, from 27 studies in 22 countries, on whom individual-level risk factor data were pooled and original mammographic images were re-read for ICMD to obtain standardized comparable MD data. In the present article, we present (i) the rationale for this consortium; (ii) characteristics of the studies and women included; and (iii) study methodology to obtain comparable MD data from original re-read films. We also highlight the risk factor heterogeneity captured by such an effort and, thus, the unique insight the pooled study promises to offer through wider exposure ranges, different confounding structures and enhanced power for sub-group analyses. (C) 2015 Elsevier Ltd. All rights reserved.
dc.language.isoeng
dc.subjectİç Hastalıkları
dc.subjectOnkoloji
dc.subjectSosyal ve Beşeri Bilimler
dc.subjectSosyoloji
dc.subjectDahili Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectSosyal Bilimler (SOC)
dc.subjectSosyal Bilimler Genel
dc.subjectKAMU, ÇEVRE VE İŞ SAĞLIĞI
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectONKOLOJİ
dc.titleInternational Consortium on Mammographic Density: Methodology and population diversity captured across 22 countries
dc.typeMakale
dc.relation.journalCANCER EPIDEMIOLOGY
dc.contributor.departmentUniversity Of Toronto , ,
dc.identifier.volume40
dc.identifier.startpage141
dc.identifier.endpage151
dc.contributor.firstauthorID2503228


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