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AmpC beta-lactamase in an Escherichia coli clinical isolate confers resistance to expanded-spectrum cephalosporins

dc.contributor.authorNaas, T
dc.contributor.authorNordmann, P
dc.contributor.authorNazic, H
dc.contributor.authorPoirel, L
dc.contributor.authorLeotard, S
dc.contributor.authorMammeri, H
dc.date.accessioned2021-03-04T11:20:49Z
dc.date.available2021-03-04T11:20:49Z
dc.date.issued2004
dc.identifier.citationMammeri H., Nazic H., Naas T., Poirel L., Leotard S., Nordmann P., "AmpC beta-lactamase in an Escherichia coli clinical isolate confers resistance to expanded-spectrum cephalosporins", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, cilt.48, sa.10, ss.4050-4053, 2004
dc.identifier.issn0066-4804
dc.identifier.otherav_71ddde9d-10ac-4dbe-8ac3-7cee3e379596
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/78381
dc.identifier.urihttps://doi.org/10.1128/aac.48.10.4050-4053.2004
dc.description.abstractCloning, sequencing, and biochemical analysis identified a novel AmpC-type beta-lactamase conferring resistance to extended-spectrum cephalosporins in an Escherichia coli clinical isolate. This enzyme, exhibiting 14 amino acid substitutions compared to a reference AmpC cephallosporinase of E. coli, hydrolyzed ceftazidime and cefepime significantly.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectSağlık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMikrobiyoloji
dc.titleAmpC beta-lactamase in an Escherichia coli clinical isolate confers resistance to expanded-spectrum cephalosporins
dc.typeMakale
dc.relation.journalANTIMICROBIAL AGENTS AND CHEMOTHERAPY
dc.contributor.department, ,
dc.identifier.volume48
dc.identifier.issue10
dc.identifier.startpage4050
dc.identifier.endpage4053
dc.contributor.firstauthorID172813


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