THE VALUE OF LABIAL BIOPSY IN THE DIFFERENTIAL DIAGNOSIS OF SARCOIDOSIS AND SJOGREN'S SYDROME AND IMMUNOHISTOCHEMICAL ANALYSIS

Abstract

The aim of this study was the evaluation of the value of labial biopsy in the differential diagnosis of sarcoidosis and Sjogren's Syndrome and the value of immunohistochemical markers such as CD3, CD4, CD8, and CD20 at the immunopathogenesis. Fifteen labial salivary gland biopsies from patients affected by primary Sjogren's syndrome, and 15 labial salivary gland biopsies from patients affected by sarcoidosis, were included in the study. In all patients, biopsies were carried out as a diagnostic procedure either for sicca syndrome or sarcoidosis.