dc.contributor.author | Yilmazer, Selma | |
dc.contributor.author | Gezen-Ak, Duygu | |
dc.contributor.author | Dursun, Erdinc | |
dc.date.accessioned | 2021-03-04T11:58:43Z | |
dc.date.available | 2021-03-04T11:58:43Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | Dursun E., Gezen-Ak D., Yilmazer S., "A Novel Perspective for Alzheimer's Disease: Vitamin D Receptor Suppression by Amyloid-beta and Preventing the Amyloid-beta Induced Alterations by Vitamin D in Cortical Neurons", JOURNAL OF ALZHEIMERS DISEASE, cilt.23, sa.2, ss.207-219, 2011 | |
dc.identifier.issn | 1387-2877 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_750c58be-9b63-4ac8-a17d-08b7862c7200 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/80422 | |
dc.identifier.uri | https://doi.org/10.3233/jad-2010-101377 | |
dc.description.abstract | Amyloid-beta (A beta) is the core component of amyloid plaques of Alzheimer's disease (AD). The effects of A beta include damage to neuronal plasma membrane, disruption of Ca2+ homeostasis, and alterations of neurotrophic factor levels. The aim of this study was to determine the effects of A beta treatment on vitamin D receptor (VDR), L-type voltage sensitive calcium channels A1C (LVSCC A1C), NGF, and observing the effects of vitamin D treatment on A beta induced alterations in primary cortical neurons. As to the latter, we aimed to test the suggested neuroprotective role of vitamin D as a neglected neurosteroid. | |
dc.language.iso | eng | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Temel Bilimler | |
dc.subject | NEUROSCIENCES | |
dc.subject | Sinirbilim ve Davranış | |
dc.subject | Yaşam Bilimleri | |
dc.title | A Novel Perspective for Alzheimer's Disease: Vitamin D Receptor Suppression by Amyloid-beta and Preventing the Amyloid-beta Induced Alterations by Vitamin D in Cortical Neurons | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF ALZHEIMERS DISEASE | |
dc.contributor.department | İstanbul Üniversitesi , , | |
dc.identifier.volume | 23 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 207 | |
dc.identifier.endpage | 219 | |
dc.contributor.firstauthorID | 6276 | |