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dc.contributor.authorSonmez, H
dc.contributor.authorOcisik, N
dc.contributor.authorKokoglu, E
dc.contributor.authorSuer, S
dc.date.accessioned2021-03-04T13:25:32Z
dc.date.available2021-03-04T13:25:32Z
dc.date.issued1996
dc.identifier.citationKokoglu E., Suer S., Sonmez H., Ocisik N., "The relationship between the electrophoretic mobility of lipoproteins and coronary heart disease", RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY, cilt.91, sa.1, ss.109-116, 1996
dc.identifier.issn1078-0297
dc.identifier.othervv_1032021
dc.identifier.otherav_7c53432e-42b7-4939-820a-005972f78280
dc.identifier.urihttp://hdl.handle.net/20.500.12627/85039
dc.description.abstractLow density lipoproteins (LDL) in patients with coronary atherosclerosis have a substantially lower content of sialic acid when compared with the LDL from healthy subjects. Desialylated LDL have smaller sizes and greater electrophoretic mobilities than sialylated ones. Desialylated LDL may be responsible for the accelerated development of foam cells in atherosclerosis. In the present study, we investigated a relationship between the electrophoretic mobility of lipoproteins and the number of significantly obstructed vessels in patients with coronary heart disease (CHD). Our findings indicate that when the number of significantly obstructed vessels is increased, the electrophoretic mobility of lipoproteins is high. We also investigated the possible role of serum sialidase activity on lipoprotein desialylation in patients with coronary heart disease. In patients with single vessel disease (p < 0.01) and double-triple vessel disease (p < 0.001) the mean serum sialidase activity was significantly higher than in the control group.
dc.language.isoeng
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectTemel Bilimler
dc.subjectSitogenetik
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectSağlık Bilimleri
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.titleThe relationship between the electrophoretic mobility of lipoproteins and coronary heart disease
dc.typeMakale
dc.relation.journalRESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY
dc.contributor.department, ,
dc.identifier.volume91
dc.identifier.issue1
dc.identifier.startpage109
dc.identifier.endpage116
dc.contributor.firstauthorID117048


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