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dc.contributor.authorSen, F.
dc.contributor.authorEkenel, MELTEM
dc.contributor.authorKilic, L.
dc.contributor.authorToz, B.
dc.contributor.authorGurdal, A.
dc.contributor.authorBaşaran, Mevhibe
dc.contributor.authorOz, F.
dc.contributor.authorYildiz, I.
dc.contributor.authorBavbek, S.
dc.contributor.authorCamlica, H.
dc.contributor.authorOflaz, H.
dc.date.accessioned2021-03-04T13:28:37Z
dc.date.available2021-03-04T13:28:37Z
dc.date.issued2013
dc.identifier.citationSen F., Yildiz I., Başaran M., Ekenel M., Oz F., Kilic L., Toz B., Gurdal A., Camlica H., Bavbek S., et al., "Impaired coronary flow reserve in metastatic cancer patients treated with sunitinib", JOURNAL OF BUON, cilt.18, sa.3, ss.775-781, 2013
dc.identifier.issn1107-0625
dc.identifier.othervv_1032021
dc.identifier.otherav_7c8f9ed0-203c-46a7-808c-1a0ddb76dbe8
dc.identifier.urihttp://hdl.handle.net/20.500.12627/85189
dc.description.abstractPurpose: Hypertension is one of the major side effects of sunitinib, an angiogenesis inhibitor used in the treatment of metastatic renal cell carcinomas (mRCC) and gastrointestinal stromal tumors (GIST). Endothelial dysfunction, an early and reversible event in the pathogenesis of atherosclerosis, is suggested to be one of the possible underlying mechanisms of hypertension caused by angiogenesis inhibitors. Coronary flow reserve (CFR) measurement by trans-thoracic Doppler echocardiography (TTDE) reflects coronary microvascular and endothelial functions, as a cheaper and an easy screening test. We have used TTDE to evaluate endothelial function and coronary microvascular function in mRCC and GIST patients under sunitinib treatment.
dc.language.isoeng
dc.subjectOnkoloji
dc.subjectSağlık Bilimleri
dc.subjectİç Hastalıkları
dc.subjectDahili Tıp Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectONKOLOJİ
dc.titleImpaired coronary flow reserve in metastatic cancer patients treated with sunitinib
dc.typeMakale
dc.relation.journalJOURNAL OF BUON
dc.contributor.departmentİstanbul Teknik Üniversitesi , Maden ,
dc.identifier.volume18
dc.identifier.issue3
dc.identifier.startpage775
dc.identifier.endpage781
dc.contributor.firstauthorID88887


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