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Niemann-Pick type C fibroblasts have a distinct microRNA profile related to lipid metabolism and certain cellular components

dc.contributor.authorLaaksonen, Reijo
dc.contributor.authorKomurcu-Bayrak, Evrim
dc.contributor.authorLehtimaki, Terho
dc.contributor.authorErginel-Unaltuna, Nihan
dc.contributor.authorOzsait, BİLGE ŞADAN
dc.contributor.authorLevula, Mari
dc.contributor.authorKAHONEN, Mika
dc.contributor.authorRai, Myriam
dc.date.accessioned2021-03-04T14:26:10Z
dc.date.available2021-03-04T14:26:10Z
dc.identifier.citationOzsait B. Ş. , Komurcu-Bayrak E., Levula M., Erginel-Unaltuna N., KAHONEN M., Rai M., Lehtimaki T., Laaksonen R., "Niemann-Pick type C fibroblasts have a distinct microRNA profile related to lipid metabolism and certain cellular components", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, cilt.403, ss.316-321, 2010
dc.identifier.issn0006-291X
dc.identifier.othervv_1032021
dc.identifier.otherav_818b477c-53ac-4274-b3da-07a5e36af013
dc.identifier.urihttp://hdl.handle.net/20.500.12627/88293
dc.identifier.urihttps://doi.org/10.1016/j.bbrc.2010.11.026
dc.description.abstractMicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression at post-transcriptional level. Dysregulation of miRNA expression may lead to severe pathophysiologies in human cells. Niemann-Pick type C (NPC) disease is a complex lipid storage disease characterized by late endosomal-lysosomal accumulation of multiple lipid molecules. Our aim was to characterize the miRNA profile in NPC fibroblasts as they may play an active role in the NPC disease associated changes in the cellular physiology.
dc.language.isoeng
dc.subjectBiyofizik
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectBİYOFİZİK
dc.subjectBiyoloji ve Biyokimya
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectTemel Bilimler
dc.subjectSitogenetik
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri
dc.subjectBiyokimya
dc.titleNiemann-Pick type C fibroblasts have a distinct microRNA profile related to lipid metabolism and certain cellular components
dc.typeMakale
dc.relation.journalBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
dc.contributor.departmentTampere University Of Technology , ,
dc.identifier.volume403
dc.identifier.startpage316
dc.identifier.endpage321
dc.contributor.firstauthorID28333


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