dc.contributor.author | Demirkiran, I. | |
dc.contributor.author | Kemik, A. S. | |
dc.contributor.author | Dulger, A. C. | |
dc.contributor.author | Ebinc, S. | |
dc.contributor.author | Kemik, O. | |
dc.contributor.author | Begenik, H. | |
dc.contributor.author | Emre, H. | |
dc.date.accessioned | 2021-03-02T20:57:53Z | |
dc.date.available | 2021-03-02T20:57:53Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Begenik H., Kemik A. S. , Emre H., Dulger A. C. , Demirkiran I., Ebinc S., Kemik O., "The association between serum Dickkopf-1 levels and esophageal squamous cell carcinoma", HUMAN & EXPERIMENTAL TOXICOLOGY, cilt.33, sa.8, ss.785-788, 2014 | |
dc.identifier.issn | 0960-3271 | |
dc.identifier.other | av_04aa4de9-aecb-4884-8b90-b8e00e09111c | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/9050 | |
dc.identifier.uri | https://doi.org/10.1177/0960327113510537 | |
dc.description.abstract | Serum Dickkopf-1 (DKK-1) is elevated in many malignancies and is an important indicator of malignant potential. However, its significance in esophageal squamous cell cancer (ESCC) has not yet been clarified. We hypothesized a role for DKK-1 in patients with ESCC. The study consisted of 90 ESCC patients and 85 healthy controls. After diagnosis, the level of DKK-1 was measured in the serum samples by enzyme-linked immunosorbent assay and the levels of DKK-1 were much higher in the ESCC patients than in the healthy control group (p < 0.0001). For serum DKK-1, the sensitivity and specificity of the assay were 70 and 80%, respectively. The preoperative serum DKK-1 level was elevated in the ESCC patients. Although serum DKK-1 is not a specific biomarker for ESCC, it might be a useful marker for the diagnosis and treatment of ESCC. | |
dc.language.iso | eng | |
dc.subject | Temel Bilimler | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Meslek Bilimleri | |
dc.subject | Farmasötik Toksikoloji | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Farmakoloji ve Toksikoloji | |
dc.subject | Eczacılık | |
dc.subject | TOKSİKOLOJİ | |
dc.title | The association between serum Dickkopf-1 levels and esophageal squamous cell carcinoma | |
dc.type | Makale | |
dc.relation.journal | HUMAN & EXPERIMENTAL TOXICOLOGY | |
dc.contributor.department | Van Yüzüncü Yıl Üniversitesi , , | |
dc.identifier.volume | 33 | |
dc.identifier.issue | 8 | |
dc.identifier.startpage | 785 | |
dc.identifier.endpage | 788 | |
dc.contributor.firstauthorID | 215932 | |