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ESTIMATION OF THE ORGAN ABSORBED DOSES AND EFFECTIVE DOSE FROM Ga-68-PSMA-11 PET SCAN

dc.contributor.authorYeyin, Nami
dc.contributor.authorKabasakal, Levent
dc.contributor.authorAraman, Ahmet
dc.contributor.authorDemirci, Emine Meltem
dc.contributor.authorOcak, Meltem
dc.contributor.authorToklu, Turkay
dc.contributor.authorAlan-Selcuk, Nalan
dc.date.accessioned2021-03-04T15:10:37Z
dc.date.available2021-03-04T15:10:37Z
dc.date.issued2018
dc.identifier.citationDemirci E. M. , Toklu T., Yeyin N., Ocak M., Alan-Selcuk N., Araman A., Kabasakal L., "ESTIMATION OF THE ORGAN ABSORBED DOSES AND EFFECTIVE DOSE FROM Ga-68-PSMA-11 PET SCAN", RADIATION PROTECTION DOSIMETRY, cilt.182, sa.4, ss.518-524, 2018
dc.identifier.issn0144-8420
dc.identifier.othervv_1032021
dc.identifier.otherav_856064e7-252f-494e-b68e-975abb14f564
dc.identifier.urihttp://hdl.handle.net/20.500.12627/90692
dc.identifier.urihttps://doi.org/10.1093/rpd/ncy111
dc.description.abstractGa-68-PSMA-11PET/CT has been proven to have high clinical value for imaging of prostate cancer and rapidly gained popularity. In this study, we aimed to investigate absorbed doses of Ga-68-PSMA-11. Seven patients (mean age = 66.9 +/- 6.6 years, range: 57-79 years) were enrolled in the study. Whole body PET images were acquired with multiple time points. MIRD method, NUKFIT and OLINDA/EXM software were used for dosimetry calculations. Kidneys, bladder wall, salivary and lacrimal glands received the highest absorbed dose. Estimated absorbed doses to these organs after injection of 150 MBq Ga-68-PSMA-11 were 37.0, 12.6, 14.4 and 6.3 mSv, respectively. Effective dose from PET scanning with 150 MBq injected Ga-68-PSMA-11 was 2.5 mSv. In conclusion, Ga-68-PSMA- 11 has a favorable dosimetry profile similar to the Ga-68 labeled octreotide analogs, which are used safely in routine clinical practices for many years. No adverse effects were reported. The kidneys were the dose-limiting organs.
dc.language.isoeng
dc.subjectÇevre Mühendisliği
dc.subjectTemel Bilimler
dc.subjectMühendislik ve Teknoloji
dc.subjectNükleer Fizik
dc.subjectÇEVRE BİLİMLERİ
dc.subjectÇevre / Ekoloji
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectKAMU, ÇEVRE VE İŞ SAĞLIĞI
dc.subjectSosyal Bilimler Genel
dc.subjectSosyal Bilimler (SOC)
dc.subjectNÜKLEAR BİLİMİ VE TEKNOLOJİSİ
dc.subjectFizik
dc.subjectTıp
dc.subjectTemel Bilimler (SCI)
dc.subjectRADYOLOJİ, NÜKLEER TIP ve MEDİKAL GÖRÜNTÜLEME
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectNükleer Tıp
dc.subjectSosyal ve Beşeri Bilimler
dc.subjectSosyoloji
dc.subjectTarımsal Bilimler
dc.titleESTIMATION OF THE ORGAN ABSORBED DOSES AND EFFECTIVE DOSE FROM Ga-68-PSMA-11 PET SCAN
dc.typeMakale
dc.relation.journalRADIATION PROTECTION DOSIMETRY
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume182
dc.identifier.issue4
dc.identifier.startpage518
dc.identifier.endpage524
dc.contributor.firstauthorID82080


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