dc.contributor.author | Aydin, S | |
dc.contributor.author | ÖZARAS, Reşat | |
dc.contributor.author | OZCELIK, Derviş | |
dc.contributor.author | Uzun, Hafize | |
dc.contributor.author | GÜREL, Z | |
dc.date.accessioned | 2021-03-04T17:19:36Z | |
dc.date.available | 2021-03-04T17:19:36Z | |
dc.identifier.citation | OZCELIK D., ÖZARAS R., GÜREL Z., Uzun H., Aydin S., "Copper-mediated oxidative stress in rat liver", BIOLOGICAL TRACE ELEMENT RESEARCH, cilt.96, ss.209-215, 2003 | |
dc.identifier.issn | 0163-4984 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_85b08278-8d94-487c-bbf8-a3aac27b0b1e | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/90892 | |
dc.identifier.uri | https://doi.org/10.1385/bter:96:1-3:209 | |
dc.description.abstract | Copper is an essential trace element with various biological functions. Excess copper, however, is extremely toxic, leading to many pathological conditions that are consistent with oxidative damage to membranes and molecules. Exposure to high levels of copper results in various changes in the tissues. In liver, hypertrophy of hepatocytes, hepatitis, hepatocellular necrosis, and hepatocellular death are the results. Lipid peroxidation causes dysfunction in the cell membrane, decreased fluidity, inactivation of receptors and enzymes, and changes ion permeability. In this study, we aimed to determine the effect of copper on oxidative and antioxidative substances in plasma and liver tissue in a rat model. | |
dc.language.iso | eng | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | İç Hastalıkları | |
dc.subject | Endokrinoloji ve Metabolizma Hastalıkları | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Moleküler Biyoloji ve Genetik | |
dc.subject | Sitogenetik | |
dc.subject | Temel Bilimler | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp | |
dc.subject | ENDOKRİNOLOJİ VE METABOLİZMA | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Moleküler Biyoloji ve Genetik | |
dc.subject | BİYOKİMYA VE MOLEKÜLER BİYOLOJİ | |
dc.title | Copper-mediated oxidative stress in rat liver | |
dc.type | Makale | |
dc.relation.journal | BIOLOGICAL TRACE ELEMENT RESEARCH | |
dc.contributor.department | İstanbul Üniversitesi , , | |
dc.identifier.volume | 96 | |
dc.identifier.startpage | 209 | |
dc.identifier.endpage | 215 | |
dc.contributor.firstauthorID | 19257 | |