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Arg25Pro (c.915G > C) polymorphism of transforming growth factor beta 1 gene suggests an association with increased risk for Hashimoto's thyroiditis

dc.contributor.authorDegirmencioglu, Sevgin
dc.contributor.authorBaki, Merve
dc.contributor.authorVural, Pervin
dc.contributor.authorKARADAG, Berrin
dc.contributor.authorUysal, Mujdat
dc.contributor.authorDogru-Abbasoglu, Semra
dc.contributor.authorOZDERYA, Aysenur
dc.date.accessioned2021-03-04T17:55:47Z
dc.date.available2021-03-04T17:55:47Z
dc.date.issued2015
dc.identifier.citationVural P., Degirmencioglu S., Dogru-Abbasoglu S., Baki M., OZDERYA A., KARADAG B., Uysal M., "Arg25Pro (c.915G > C) polymorphism of transforming growth factor beta 1 gene suggests an association with increased risk for Hashimoto's thyroiditis", INTERNATIONAL IMMUNOPHARMACOLOGY, cilt.28, ss.521-524, 2015
dc.identifier.issn1567-5769
dc.identifier.othervv_1032021
dc.identifier.otherav_8808c9cb-5ba3-43c7-922a-b9b12f9bff9e
dc.identifier.urihttp://hdl.handle.net/20.500.12627/92342
dc.identifier.urihttps://doi.org/10.1016/j.intimp.2015.07.019
dc.description.abstractBackground: The etiopathogenesis of Hashimoto's thyroiditis (HT) - has not been clearly elucidated although the role of chronic inflammation, endothelial dysfunction, and imbalance between pro- and anti-inflammatory cytokines has been established. Transforming growth factor beta 1 (TGF beta 1) is required to maintain immune homeostasis, and is implicated in lymphocyte infiltration, production of autoantibodies and thyrocyte destruction seen in patients with HT.
dc.language.isoeng
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectSağlık Bilimleri
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectİmmünoloji
dc.titleArg25Pro (c.915G > C) polymorphism of transforming growth factor beta 1 gene suggests an association with increased risk for Hashimoto's thyroiditis
dc.typeMakale
dc.relation.journalINTERNATIONAL IMMUNOPHARMACOLOGY
dc.contributor.departmentIstanbul Sisli Hamidiye Etfal Training & Research Hospital , ,
dc.identifier.volume28
dc.identifier.issue1
dc.identifier.startpage521
dc.identifier.endpage524
dc.contributor.firstauthorID44499


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