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Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy

dc.contributor.authorMcCann, Liza
dc.contributor.authorKingsbury, Daniel
dc.contributor.authorJoos, Rik
dc.contributor.authorHoughton, Kristin
dc.contributor.authorTerreri, Maria
dc.contributor.authorHarel, Liora
dc.contributor.authorGerloni, Valeria
dc.contributor.authorSchneider, Rayfel
dc.contributor.authorRutkowska-Sak, Lidia
dc.contributor.authorRuperto, Nicolino
dc.contributor.authorBrachat, Arndt H.
dc.contributor.authorGrom, Alexei A.
dc.contributor.authorWulffraat, Nico
dc.contributor.authorBrunner, Hermine I.
dc.contributor.authorQuartier, Pierre
dc.contributor.authorBrik, Riva
dc.contributor.authorOzdogan, Huri
dc.contributor.authorNirmala, Nanguneri R.
dc.contributor.authorLovell, Daniel J.
dc.contributor.authorMartini, Alberto
dc.contributor.authorAbrams, Ken
dc.contributor.authorGram, Hermann
dc.contributor.authorValentin, Marie-Anne
dc.contributor.authorSchumacher, Martin
dc.contributor.authorBek, Stephan
dc.contributor.authorLopez-Benitez, Jorge M.
dc.date.accessioned2021-03-04T18:12:35Z
dc.date.available2021-03-04T18:12:35Z
dc.identifier.citationBrachat A. H. , Grom A. A. , Wulffraat N., Brunner H. I. , Quartier P., Brik R., McCann L., Ozdogan H., Rutkowska-Sak L., Schneider R., et al., "Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy", ARTHRITIS RESEARCH & THERAPY, cilt.19, 2017
dc.identifier.issn1478-6354
dc.identifier.otherav_8979a0ab-4ef7-4805-9ae7-010491bbafae
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/93236
dc.identifier.urihttps://doi.org/10.1186/s13075-016-1212-x
dc.description.abstractBackground: Canakinumab is a human anti-interleukin-1 beta (IL-1 beta) monoclonal antibody neutralizing IL-1 beta-mediated pathways. We sought to characterize the molecular response to canakinumab and evaluate potential markers of response using samples from two pivotal trials in systemic juvenile idiopathic arthritis (SJIA).
dc.language.isoeng
dc.subjectİmmünoloji ve Romatoloji
dc.subjectDahili Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectROMATOLOJİ
dc.subjectİç Hastalıkları
dc.titleEarly changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy
dc.typeMakale
dc.relation.journalARTHRITIS RESEARCH & THERAPY
dc.contributor.departmentNovartis , ,
dc.identifier.volume19
dc.contributor.firstauthorID240187


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