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dc.contributor.authorTANRIVERDİ, Taner
dc.contributor.authorKAÇIRA, Tibet
dc.contributor.authorYURDAKUL, Fatma
dc.contributor.authorGUMUSTAS, K
dc.contributor.authorUzun, Hafize
dc.contributor.authorKAYNAR, MY
dc.contributor.authorKAFADAR, M
dc.date.accessioned2021-03-04T18:13:24Z
dc.date.available2021-03-04T18:13:24Z
dc.date.issued2005
dc.identifier.citationKAYNAR M., TANRIVERDİ T., KAFADAR M., KAÇIRA T., YURDAKUL F., Uzun H., GUMUSTAS K., "YKL-40 levels in the cerebrospinal fluid and serum of patients with aneurysmal subarachnoid hemorrhage: Preliminary results", JOURNAL OF CLINICAL NEUROSCIENCE, cilt.12, ss.754-757, 2005
dc.identifier.issn0967-5868
dc.identifier.othervv_1032021
dc.identifier.otherav_8991a2a5-72bc-47fb-b3f2-1cac37a973ed
dc.identifier.urihttp://hdl.handle.net/20.500.12627/93290
dc.identifier.urihttps://doi.org/10.1016/j.jocn.2005.06.001
dc.description.abstractYKL-40 is a newly discovered matrix protein thought to be secreted during the acute stages of inflammation. Clinical studies have revealed that YKL-40 has growth factor and potent migration factor activity for cells involved in inflammation and tissue remodeling processes. It has recently been speculated that YKL-40 may serve as a specific serologic marker of neutrophil function at the site of acute tissue inflammation. We aimed to quantify the levels of YKL-40 in both cerebrospinal fluid and serum of ten consecutive patients with aneurysmal subarachnoid hemorrhage and to speculate on the origin of this glycoprotein. The levels were also compared with ten control patients with hydrocephalus. We found that patients with aneurysmal subarachnoid hemorrhage had significantly higher YKL-40 levels in both cerebrospinal fluid and serum than controls. The authors believe that YKL-40 is expressed in cerebrospinal fluid due to stress on neural structures while a damaged blood-brain barrier allows entry of neutrophils and macrophages from the systemic circulation. (c) 2005 Elsevier Ltd. All rights reserved.
dc.language.isoeng
dc.subjectDahili Tıp Bilimleri
dc.subjectNöroloji
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectSinirbilim ve Davranış
dc.subjectNEUROSCIENCES
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKLİNİK NEUROLOJİ
dc.titleYKL-40 levels in the cerebrospinal fluid and serum of patients with aneurysmal subarachnoid hemorrhage: Preliminary results
dc.typeMakale
dc.relation.journalJOURNAL OF CLINICAL NEUROSCIENCE
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume12
dc.identifier.issue7
dc.identifier.startpage754
dc.identifier.endpage757
dc.contributor.firstauthorID19199


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