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dc.contributor.authorKupik, Osman
dc.contributor.authorEren, Gulnihan
dc.contributor.authorGÜNDOĞDU, HASAN
dc.contributor.authorARPA, MEDENİ
dc.contributor.authorAsa, Sertac
dc.contributor.authorBozkurt, Mehmet
dc.date.accessioned2021-03-04T19:34:32Z
dc.date.available2021-03-04T19:34:32Z
dc.date.issued2020
dc.identifier.citationKupik O., Bozkurt M., Asa S., Eren G., GÜNDOĞDU H., ARPA M., "Do Volume-Based and Metabolic 18F FDG PET/CT Parameters Identify Groups at Risk for Poor Prognosis in Patients with Newly Diagnosed Metastatic and Non-Metastatic Non-Small Cell Lung Cancer?", UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, cilt.30, ss.162-170, 2020
dc.identifier.issn1306-133X
dc.identifier.otherav_906f4d2e-472f-4ff3-8423-14960c82d2d9
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/97493
dc.identifier.urihttps://doi.org/10.4999/uhod.204173
dc.description.abstractTo determine the relationship between F-18 FDG PET/CT parameters of the primary tumor/nodal metastasis/distant metastasis and overall survival (OS) of patients with newly diagnosed non-small cell lung cancer (NSCLC). Data from 159 patients with newly diag-nosed NSCLC who underwent pretreatment 18F FDG PET/CT were analyzed. The SUVmax, SUVmean, the metabolic tumor volume (MTV), and total lesion glycolysis (TLG) of the primary tumor, lymph node metastasis, and distant metastasis were measured. The total MTV and total TLG were calculated. The optimal cut-off values of the F-18 FDG PET/CT parameters were determined using receiver operating characteristics curve analysis. Kaplan-Meier curves were used to determine OS. There were a total of 101 deaths during the follow-up (range, 3.7-54.2 months). The median OS was 26.4 months for the entire group, 11.8 months for patients with metas-tasis, and 41 months for patients with no metastasis (p= 328 and TLG < 328 were 32% and 80%, respectively. Independent predictors for OS were found as SUVmaxN in the group of patients with distant metastasis, and SUVmax, MTV of the primary tumor (MTVT), and lymph node size (LNsize) in the group of patients without distant metastasis. F-18 FDG PET/CT may distinguish patients with high risk for poor prognosis in patients with and without metastasis.
dc.language.isoeng
dc.subjectOnkoloji
dc.subjectONKOLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.titleDo Volume-Based and Metabolic 18F FDG PET/CT Parameters Identify Groups at Risk for Poor Prognosis in Patients with Newly Diagnosed Metastatic and Non-Metastatic Non-Small Cell Lung Cancer?
dc.typeMakale
dc.relation.journalUHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI
dc.contributor.departmentRecep Tayyip Erdoğan Üniversitesi , ,
dc.identifier.volume30
dc.identifier.issue3
dc.identifier.startpage162
dc.identifier.endpage170
dc.contributor.firstauthorID2276637


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