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dc.contributor.authorSIMSEK, O
dc.contributor.authorCOBANOGLU, Seçkin
dc.contributor.authorIMER, M
dc.contributor.authorKUTLU, K
dc.contributor.authorSencer, Altay
dc.contributor.authorGORGULU, A
dc.date.accessioned2021-03-04T19:46:52Z
dc.date.available2021-03-04T19:46:52Z
dc.date.issued1998
dc.identifier.citationGORGULU A., IMER M., SIMSEK O., Sencer A., KUTLU K., COBANOGLU S., "The effect of aprotinin on extraneural scarring in peripheral nerve surgery: An experimental study", ACTA NEUROCHIRURGICA, cilt.140, ss.1303-1307, 1998
dc.identifier.issn0001-6268
dc.identifier.otherav_916cb996-f82f-4b8b-8fb1-2eaa350ce76a
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/98114
dc.identifier.urihttps://doi.org/10.1007/s007010050254
dc.description.abstractExtraneural scarring is one of the factors negatively influencing the result of peripheral nerve surgery. Many organic materials have been used to prevent fibrosis. The effect of aprotinin on peripheral nerve scarring in rats was investigated in this study. Three types of surgical intervention were carried out; namely external neurolysis (I), abrasive injury (II), and anastomosis (III). The coded samples which consisted of pure collagen fibers soaked with aprotinin or phosphate-buffered saline were applied around the left sciatic nerves of rats whereas only sham operations were performed on the right sciatic nerves. Animals were sacrificed after 4 or 6 weeks. Neurological examination, gross evaluation of extraneural fibrosis, and histological study were undertaken. The results have demonstrated that aprotinin is a promising agent in the prevention of extraneural scarring.
dc.language.isoeng
dc.subjectCerrahi Tıp Bilimleri
dc.subjectTıp
dc.subjectNöroloji
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectCERRAHİ
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKLİNİK NEUROLOJİ
dc.titleThe effect of aprotinin on extraneural scarring in peripheral nerve surgery: An experimental study
dc.typeMakale
dc.relation.journalACTA NEUROCHIRURGICA
dc.contributor.departmentTrakya Üniversitesi , ,
dc.identifier.volume140
dc.identifier.issue12
dc.identifier.startpage1303
dc.identifier.endpage1307
dc.contributor.firstauthorID59840


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